Abstract
The reaction of 5,6-diamino-1,3-dimethyluracil with 1,3-diaryl-2,3-dibromopropan-1-ones gave β-(5-amino-6-imino-1,3-dimethyluracil)chalcones, and conditions for their cyclocondensation to pyrimidinodiazepines were found. For substantiation of the reaction mechanism, the reaction of the diamine with other halogen derivatives of chalcones was studied. The IR, UV, and mass spectra of the synthesized compounds and their condensation products are discussed.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 947–954, July, 1992.
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Orlov, V.D., Kolos, N.N., Tuéni, M. et al. Reactions of 5,6-diamino-1,3-dimethyluracil with halogen derivatives of chalcones. Chem Heterocycl Compd 28, 788–794 (1992). https://doi.org/10.1007/BF00474494
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DOI: https://doi.org/10.1007/BF00474494