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Formation of derivatives of thiazoline by the reaction of thiourea with 2-bromo-3-aminopropionic acid

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Depending on the conditions employed, thiourea reacts with the hydrobromide of 2-bromo-3-aminopropionic acid to give a dihydrobromide or an internal salt S-(2-amino-1-carboxyethyl)isothiourea. This compound can also lose ammonia to give a thiazoline derivative.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1687–1689, December, 1986.

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Golubev, A.A., Semenenko, M.N., Mandrugin, A.A. et al. Formation of derivatives of thiazoline by the reaction of thiourea with 2-bromo-3-aminopropionic acid. Chem Heterocycl Compd 22, 1367–1369 (1986). https://doi.org/10.1007/BF00474362

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  • DOI: https://doi.org/10.1007/BF00474362

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