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N-glycosides. 7. Synthesis of 4,5′-anhydro-3-(2′,2′-O-isopropylidene-Β-D-ribofuranosyl)-4-hydroxyhexahydropyrimidine-2-thiones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Reaction of 2,3-O-isopropylideneribofuranosylamine p-toluene-sulfonate with Β-isothiocyantoaldehydes in the presence of bases leads to the formation of 4,5′-anhydro-3-(2′,3′-O-isopropylidene-Β-D-ribofuranosyl)-4-hydroxyhexahydropyrimidine-2-thiones, whose steric structure was established by PMR spectroscopy.

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Authors and Affiliations

  1. M. V. Lomonosov Institute of Fine Chemical Technology, 119831, Moscow

    A. D. Shutalev, L. L. Ignatova & B. V. Unkovskii

Authors
  1. A. D. Shutalev
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  2. L. L. Ignatova
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  3. B. V. Unkovskii
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Additional information

For Communication 6, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1652–1657, December, 1986.

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Shutalev, A.D., Ignatova, L.L. & Unkovskii, B.V. N-glycosides. 7. Synthesis of 4,5′-anhydro-3-(2′,2′-O-isopropylidene-Β-D-ribofuranosyl)-4-hydroxyhexahydropyrimidine-2-thiones. Chem Heterocycl Compd 22, 1336–1341 (1986). https://doi.org/10.1007/BF00474355

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  • DOI: https://doi.org/10.1007/BF00474355

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