Skip to main content
Log in

Analogs of pyrimidine mono- and polynucleotides

I. Diphosphates of N1-(1,4-dihydroxy-2-butyl) derivatives of uracil and thymine

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Phosphorylation of N1-(1,4-dihydroxy-2-butyl) derivatives of uracil and thymine with polyphosphoric acid or Β-cyanoethyl phosphate in the presence of dicyclohexylcarbodiimide gives the corresponding diphosphates as the chief reaction products.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature cited

  1. S. A. Giller, R. A. Zhuk, A. é. Berzinya, L. T. Kaulinya, and L. A. Sherin', Khim. Geterotsikl. Soedin., 1662 (1974).

  2. R. H. Hall and H. G. Khorana, J. Amer. Chem. Soc., 77, 1871 (1955).

    Google Scholar 

  3. G. M. Tener, J. Amer. Chem. Soc., 83, 159 (1961).

    Google Scholar 

  4. A. Bloch, M. N. Fleisher, R. E. Manne, and R. H. Hall, J. Med. Chem., 9, 886 (1966).

    Google Scholar 

  5. A. Adam and J. G. Moffatt, Biochemistry, 7, 875 (1968).

    Google Scholar 

  6. J. Hynie, J. Stepan, and B. Večerek, J. Chromatography, 24, 298 (1966).

    Google Scholar 

  7. T. V. Venkstern and A. A. Baev, Absorption Spectra of Minor Bases, Their Nucleosides, Nucleotides, and some Oligoribonucleotides [in Russian], Nauka, Moscow (1965).

    Google Scholar 

  8. B. R. Baker, G. D. F. Jackson, and G. B. Chheda, J. Pharm. Sci., 54, 1617 (1965).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1671–1673, December, 1974.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Giller, S.A., Sherin', L.A., Zhuk, R.A. et al. Analogs of pyrimidine mono- and polynucleotides. Chem Heterocycl Compd 10, 1468–1470 (1974). https://doi.org/10.1007/BF00474332

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00474332

Keywords

Navigation