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Synthesis of 1-alkyl-2-arylpyrroles from aryl(3-bromo-2-methoxypropyl)ketones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Aryl(3-bromo-2-methoxypropyl)ketones have been obtained by bromination of allylarylketones using N-bromosuccinimide. When treated with primary amines, good yields of 1-alkyl-2-arylpyrroles were obtained via 1,3-dehydrobromination and subsequent opening of the tricyclic ring in the intermediate aryl(2-methoxycyclopropyl)ketones.

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Authors and Affiliations

  1. V. I. Lenin State University, Minsk

    V. L. Sorokin, A. A. Azzuz & O. G. Kulinovich

Authors
  1. V. L. Sorokin
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  2. A. A. Azzuz
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  3. O. G. Kulinovich
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 334–336, March, 1991.

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Sorokin, V.L., Azzuz, A.A. & Kulinovich, O.G. Synthesis of 1-alkyl-2-arylpyrroles from aryl(3-bromo-2-methoxypropyl)ketones. Chem Heterocycl Compd 27, 271–272 (1991). https://doi.org/10.1007/BF00474227

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  • DOI: https://doi.org/10.1007/BF00474227

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