Skip to main content
Log in

Synthesis of 1-substituted-3,3-dimethyl-3,4-dihydroisoquinolines

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The Ritter reaction between Β-substituted propionitriles and dimethylbenzylcarbinols gives 3,3-dimethyl-3,4-dihydroisoquinolines containing substituents in the 1-position corresponding to those in the starting nitrile.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature Cited

  1. E. Seegcr, W. Engel, H. Teufel, and H. Machleidt, Chem. Ber., 103, 1674 (1970).

    Google Scholar 

  2. V. S. Skhlyaev, B. B. Aleksandrov, M. I. Bakhrin, and G. I. Legotkina, USSR Inventor's Certificate No. 771,093; Byull. Isobret., No. 38, 136 (1980).

    Google Scholar 

  3. B. B. Aleksandrov, M. S. Gavrilov, M. I. Vakhrin, and V. S. Shklyaev, Khim. Geterotsikl. Soedin., No. 6, 794 (1985).

    Google Scholar 

  4. A. P. Terent'ev and E. Terent'eva, Zh. Obshch. Khim., 12, 415 (1942).

    Google Scholar 

  5. F. Whitmore, H. Mosher, R. Adams, R. Taylor, E. Chapin, C. Weisel, and W. Yanko, J. Am. Chem. Soc., 66, 725 (1944).

    Google Scholar 

  6. A. F. Bekhli and A. G. Serebryannikova, Zh. Obshch. Khim., 19, 1553 (1949).

    Google Scholar 

  7. D. Trbell, N. Shakespeare, C. Claus, and J. Bunnett, J. Am. Chem. Soc., 68, 1217 (1946).

    Google Scholar 

  8. W. Untermohlen, J. Am. Chem. Soc., 67, 1505 (1945).

    Google Scholar 

  9. C. Hurd and L. Gerschein, J. Am. Chem. Soc., 69, 2328 (1947).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 657–659, May, 1991.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Aleksandrov, B.B., Dormidontov, M.Y., Shklyaev, V.S. et al. Synthesis of 1-substituted-3,3-dimethyl-3,4-dihydroisoquinolines. Chem Heterocycl Compd 27, 523–525 (1991). https://doi.org/10.1007/BF00473999

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00473999

Keywords

Navigation