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Researches on imidazoles

XVI. Preparation of 1-methyl-4, 5-dihalogeno- and 1-methyl-2, 4, 5-trihalogenoimidazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The 1-methyl-4, 5-dihalogeno-and 1-methyl-2, 4, 5-trihalogenoimidazoles resulting from reacting N, N′-dimethyloxamide with phosphorus pentachloride or pentabromide, are formed by secondary reaction, halogenation of 1-methyl-5-halogenoimidazoles by the phosphorus pentahalides, which also halogenate other imidazoles derivatives, e. g., 1, 2-dialkyl-5-chloroimidazole and 2-alkylimidazoles at the free position in the nucleus.

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For Part XV see [1].

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Kochergin, P.M. Researches on imidazoles. Chem Heterocycl Compd 1, 265–267 (1966). https://doi.org/10.1007/BF00473607

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  • DOI: https://doi.org/10.1007/BF00473607

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