Chemistry of Heterocyclic Compounds

, Volume 23, Issue 8, pp 854–856 | Cite as

Syntheses of 2,2′-diimidazole

  • V. V. Nurgatin
  • B. M. Ginzburg
  • G. P. Sharnin
  • V. F. Polyanskii


New methods of preparation of 2,2′-diimidazole have been developed, by the reaction of ammonia with 1,1-dibromoacetaldehyde (20% yield) or with glyoxal sulfate (40%), and by the cyclization of 1,2-dihydroxyethylenediamine dihydrochloride in the presence of sodium acetate (yield 60%).


Sodium Sulfate Acetate Ammonia Organic Chemistry 
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Literature Cited

  1. 1.
    P. Mellonia, E. Dradi, and W. Logemann, J. Med. Chem., 15, 929 (1972).Google Scholar
  2. 2.
    P. Melloni, D. Fusar-Bassini, E. Dradi, and C. Confalonieri, J. Heterocycl. Chem., 11, 731 (1974).Google Scholar
  3. 3.
    A. Pinner, Ber. Chem. Ges., 17, 1977 (1884).Google Scholar
  4. 4.
    H. Debus, Liebigs Ann. Chem., 107, 199 (1858).Google Scholar
  5. 5.
    R. Behrend and H. Koelln, Liebigs Ann. Chem., 416, 230 (1918).Google Scholar
  6. 6.
    E. Duranti and C. Balsamini, Synthesis, No. 11, 815 (1974).Google Scholar
  7. 7.
    V. V. Nurgatin, B. M. Ginzburg, V. I. Kovalenko, and G. A. Marchenko, Khim. Geterotsikl. Soedin., No. 9, 1265 (1985).Google Scholar
  8. 8.
    P. Ruggli and E. Henzi, Helv. Chim. Acta, 12, 362 (1929).Google Scholar
  9. 9.
    N. B. Colthup, L. N. Daly, and S. E. Viberley, Introduction to Infrared and Raman Spectroscopy, Academic Press, New York-London (1964).Google Scholar
  10. 10.
    H. Mylo, Ber. Chem. Ges., 45, 647 (1912).Google Scholar

Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • V. V. Nurgatin
  • B. M. Ginzburg
  • G. P. Sharnin
  • V. F. Polyanskii

There are no affiliations available

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