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Chemistry of Heterocyclic Compounds

, Volume 23, Issue 8, pp 842–846 | Cite as

Reactions of derivatives of N-aryl-2-methyl-3-ethoxycarbonyl-4,5-dihydroxy-6-bromoindoles

  • A. N. Grinev
  • I. K. Sorokina
Article
  • 35 Downloads

Abstract

Some 4,5-dihydroxyindoles, with an acetoacetic ester substituent at the 7 position were used to synthesize 7-acetonyl-4,5-dihydroxyindoles. Methylation of these compounds gave 4-hydroxy-5-methoxy- and 4,5-dimethoxyindoles. On reaction with hydroxylamine, these compounds were converted to the oximes. Oxidation of 4,5-dihydroxyindoles with nitric acid gave 4,5-indolequinones.

Keywords

Oxidation Methylation Ester Organic Chemistry Nitric Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • A. N. Grinev
    • 1
  • I. K. Sorokina
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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