Chemistry of Heterocyclic Compounds

, Volume 23, Issue 8, pp 842–846 | Cite as

Reactions of derivatives of N-aryl-2-methyl-3-ethoxycarbonyl-4,5-dihydroxy-6-bromoindoles

  • A. N. Grinev
  • I. K. Sorokina


Some 4,5-dihydroxyindoles, with an acetoacetic ester substituent at the 7 position were used to synthesize 7-acetonyl-4,5-dihydroxyindoles. Methylation of these compounds gave 4-hydroxy-5-methoxy- and 4,5-dimethoxyindoles. On reaction with hydroxylamine, these compounds were converted to the oximes. Oxidation of 4,5-dihydroxyindoles with nitric acid gave 4,5-indolequinones.


Oxidation Methylation Ester Organic Chemistry Nitric Acid 
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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • A. N. Grinev
    • 1
  • I. K. Sorokina
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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