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Heterocyclic analogs of pleiadiene

XI. Synthesis of 1-(β-dialkylaminoalkyl)- and 2-aminoperimidines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The corresponding 1-β-dialkylaminoethylperimidines were obtained by the action of β-dialkylaminoethyl chloride hydrochlorides on perimidines in alkaline media. Some of the compounds obtained form substituted 2-aminoperimidines and 2-perimidone on reaction with sodium amide or alkali. 2-Morpholino- and 2-piperidino-1-methylperimidines are obtained from 1-methyl-2-chloroperimidine and morpholine or piperidine. The synthesized compounds have weak bacteriostatic, fungistatic, and tuberculostatic activity.

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Literature cited

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See [1] for communication X.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 418–421, March, 1974.

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Pozharskii, A.F., Pershina, L.P., Kashparov, I.S. et al. Heterocyclic analogs of pleiadiene. Chem Heterocycl Compd 10, 366–368 (1974). https://doi.org/10.1007/BF00472432

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  • DOI: https://doi.org/10.1007/BF00472432

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