Skip to main content
SpringerLink
Log in

Mass spectrometric study of 2-keto(thio)tetrahydropyrimidine derivatives

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The fragmentation pathways of 2-keto(thio)-6-methyl-5-carbethoxy(acetyl)-4-aryl-1,2,3,4-tetrahydropyrimidines were established using high resolution mass spectra and DADI spectra. An unusual rearrangement was observed, which involves cyclization of the aryl substituent in the 4 position with the oxygen of an ester group and elimination of a C2H5 radical.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. L. Yu. Ivanovskya, M. I. Gorfinkel, V. F. Sedova, and Z. D. Duhovenko, Org. Mass Spectrom., 7, 911 (1973).

    Google Scholar 

  2. T. Kate et al., Org. Mass Spectrom., 9, 981 (1974).

    Google Scholar 

  3. X. Hasapis et al., Tetrahedron, 35, 2087 (1979).

    Google Scholar 

  4. E. Falch, Acta Chem. Scand., 24, 137 (1970).

    Google Scholar 

  5. C. Fenselau and S. Y. Wang, Tetrahedron, 25, 2853 (1969).

    Google Scholar 

  6. L. Yu. Ivanovskaya, V. F. Sedova, M. I. Gorfinkel', and V. P. Mamaev, Izv. Sib. Otd. Akad. Nauk SSSR, Ser. Khim. Nauk, No. 4, 123 (1969).

    Google Scholar 

  7. E. L. Esmans, R. A. Domisse, and F. C. Alder-Weikeldt, Org. Mass Spectrom., 10, 854 (1975).

    Google Scholar 

  8. A. Selva, A. Gennaro, and P. Caramella, Org. Mass Spectrom., 11, 117 (1976).

    Google Scholar 

  9. G. D. Tantsyrev and V. A. Saraev, Secondary Ion and Ion-Photon Emission [in Russian], Khar'kov (1980), p. 73.

  10. P. Biginelli, Berichte, 24, 1317 (1981).

    Google Scholar 

  11. K. Folkers, H. J. Harwood, and T. B. Johnson, J. Am. Chem. Soc., 54, 3751 (1932).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. P. Lumumba Peoples' Friendship University, 117923, Moscow

    E. E. Stashenko, P. I. Zakharov, V. G. Pleshakov & B. S. Subbotin

Authors
  1. E. E. Stashenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. I. Zakharov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. G. Pleshakov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. B. S. Subbotin
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 360–365, March, 1989.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Stashenko, E.E., Zakharov, P.I., Pleshakov, V.G. et al. Mass spectrometric study of 2-keto(thio)tetrahydropyrimidine derivatives. Chem Heterocycl Compd 25, 301–305 (1989). https://doi.org/10.1007/BF00472390

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00472390

Keywords

Search

Navigation