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Indole derivatives

LXXXIII. Preparation of indole and 5-bromoindole from 2-naphthol and 6-bromo-2-naphthol

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The o-carboxycinnamic acids obtained in the oxidation of 2-naphthol and 6-bromo-2-naphthol were converted to the amides, which give indole and 5-bromoindole, respectively, under the conditions of the Hofmann reaction. Oxidation of 5-nitro-2-naphthol gives the γ-lactone of 6-nitro-2-carboxycinnamic acid rather than the acid itself.

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Authors and Affiliations

  1. D. I. Mendeleev Moscow Chemical Engineering Institute, USSR

    G. N. Petrova, V. F. Shner, L. M. Alekseeva & N. N. Suvorov

Authors
  1. G. N. Petrova
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  2. V. F. Shner
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  3. L. M. Alekseeva
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  4. N. N. Suvorov
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Additional information

See [1] for communication LXXXII.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 753–755, June, 1973.

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Petrova, G.N., Shner, V.F., Alekseeva, L.M. et al. Indole derivatives. Chem Heterocycl Compd 9, 691–694 (1973). https://doi.org/10.1007/BF00472308

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  • DOI: https://doi.org/10.1007/BF00472308

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