Chemistry of Heterocyclic Compounds

, Volume 10, Issue 9, pp 1023–1028 | Cite as

Alkylation and some physicoc hemical characteristics of 6,7- and 7,8- dihydroxycoumarins

  • V. A. Zagorevskii
  • Z. D. Kirsanova
  • I. V. Persianova
  • D. A. Zykov


The lower selectivity of the methylation of 4-methyl-7,8-dihydroxycoumarin as compared with the methylation of 6,7-dihydroxycoumarins is explained by means of the pK a values and data from the PMR and IR spectra by the slight difference in the acidity of the hydroxyl groups in the 7- and 8-positions.


Methylation Hydroxyl Organic Chemistry Acidity Alkylation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • V. A. Zagorevskii
    • 1
  • Z. D. Kirsanova
    • 1
  • I. V. Persianova
    • 1
  • D. A. Zykov
    • 1
  1. 1.Institute of PharmacologyAcademy of Medical Sciences of the USSRMoscow

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