Chemistry of Heterocyclic Compounds

, Volume 15, Issue 4, pp 413–418 | Cite as

Mass spectra of piperidines with a shielded nitrogen atom

  • A. I. Ermakov
  • Zh. K. Torosyan
  • Yu. N. Sheinker


2,2,6,6-Tetramethylpiperidines with various substituants attached to the C4 atom [R=H, OH, CN, CH2COOH, C6H5, N(CH3)2, N(COCH3)CH2C6H5, N(CH2)5, and N(CH2CH2)O] were studied by means of mass spectrometry. The peculiarities of the fragmentation of the piperidine ring with a shielded electron pair at the heteroatom as a function of the type of substituent attached to the C4, atom are discussed. The fragmentation was studied with the use of high-resolution mass spectrometry, lowvoltage mass spectra, and deuterium labeling.


Nitrogen Mass Spectrometry Mass Spectrum Organic Chemistry Nitrogen Atom 
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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • A. I. Ermakov
    • 1
  • Zh. K. Torosyan
    • 1
  • Yu. N. Sheinker
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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