Abstract
A new method for the synthesis of 8-pyridiniotheophyllinates by the action of pyridine or alkylpyridines on theophylline or 8-bromotheophylline in the presence of oxidizing agents was developed. The oxidation of 8-bromotheophylline gives the best results. This method was used to obtain 8-(2-methylpyridinio)theophyllinate, which could not be synthesized previously.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
V. N. Bobkov, T. V. Zvolinskaya, and I. I. Kuz'menko, Khim. Geterotsikl. Soedin., No. 7, 1000 (1988).
V. N. Bobkov, T. V. Zvolinskaya, and I. I. Kuz'menko, Khim. Geterotsikl. Soedin., No. 11, 1541 (1990).
D. Barton and U. D. Ollis (eds.), General Organic Chemistry [Russian translation], Khimiya, Moscow (1985), p. 15.
V. I. Khmelevskii, V. V. Pavlova, and O. I. Durnitsyna, Med. Prom. SSSR, No. 10, 39 (1966).
Author information
Authors and Affiliations
Additional information
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1535–1538, November, 1991.
Rights and permissions
About this article
Cite this article
Bobkov, V.N., Zvolinskaya, T.V. & Kuz'menko, I.I. New method for obtaining 8-pyridiniotheophyllinates. Chem Heterocycl Compd 27, 1239–1242 (1991). https://doi.org/10.1007/BF00471753
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00471753