Abstract
Methyl-substituted 1,2,4,5-tetrahydro-3H-spiro(benz-2-azepine-3,4′-piperidines) were obtained by the intramolecular cyclization of 4-allyl-4-N-benzyl(α-phenylethyl)aminopiperidines in an acidic medium. The individual isomers of 1′-benzyl-2′,5,5′-trimethyl-1,2,4,5-tetrahydro-3H-spiro(benz-2-azepine-3,4′-piperidine) were isolated, and their structures were established.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1528–1532, November, 1991.
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Kuznetsov, V.V., Lantsetov, S.V., Aliev, A.É. et al. Synthesis and structures of methyl-substituted 1,2,4,5-tetrahydro-3H-spiro(benz-2-azepine-3,4′-piperidines). Chem Heterocycl Compd 27, 1233–1237 (1991). https://doi.org/10.1007/BF00471751
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DOI: https://doi.org/10.1007/BF00471751