Chemistry of Heterocyclic Compounds

, Volume 9, Issue 7, pp 853–856 | Cite as

Oxidation and reduction of some derivatives of benzo-2,1,3-thiadiazole

  • I. A. Belen'kaya
  • N. S. Tsepova
  • Ya. L. Kostyukovskii
  • V. G. Pesin


In the reduction of 4-hydroxy-7-phenylazobenzo-2,1,3-thiadiazole and of 4-hydroxy-7-nitro-benzo-2,1, 3-thiadiazole with sodium hydrosulfite, 7-amino-4-hydroxybenzo-2,1,3-thiadiazole is obtained. The reduction of 4-hydroxybenzo-2,1,3-thiadiazole leads to 2,3-diaminophenol which forms 5-hydroxyquinoxaline with the bisulfite derivative of glyoxal. The oxidation of 4-hydroxy- and 4-aminobenzo-2,1,3-thiadiazoles with potassium dichromate in an acid medium has yielded 4,7-dioxo-4,7-dihydrobenzo-2,1,3-thiadiazole, which has been converted into 4,7-dihydroxybenzo-2,1,3-thiadiazole and 4,7-di(hydroxyimino)-4,7-dihydrobenzo-2,1,3-thiadiazole.


Oxidation Sodium Potassium Organic Chemistry Acid Medium 
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Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • I. A. Belen'kaya
    • 1
  • N. S. Tsepova
    • 1
  • Ya. L. Kostyukovskii
    • 1
  • V. G. Pesin
    • 1
  1. 1.S. M. Kirov Academy of Military MedicineLeningrad

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