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Chemistry of Heterocyclic Compounds

, Volume 9, Issue 7, pp 853–856 | Cite as

Oxidation and reduction of some derivatives of benzo-2,1,3-thiadiazole

  • I. A. Belen'kaya
  • N. S. Tsepova
  • Ya. L. Kostyukovskii
  • V. G. Pesin
Article

Abstract

In the reduction of 4-hydroxy-7-phenylazobenzo-2,1,3-thiadiazole and of 4-hydroxy-7-nitro-benzo-2,1, 3-thiadiazole with sodium hydrosulfite, 7-amino-4-hydroxybenzo-2,1,3-thiadiazole is obtained. The reduction of 4-hydroxybenzo-2,1,3-thiadiazole leads to 2,3-diaminophenol which forms 5-hydroxyquinoxaline with the bisulfite derivative of glyoxal. The oxidation of 4-hydroxy- and 4-aminobenzo-2,1,3-thiadiazoles with potassium dichromate in an acid medium has yielded 4,7-dioxo-4,7-dihydrobenzo-2,1,3-thiadiazole, which has been converted into 4,7-dihydroxybenzo-2,1,3-thiadiazole and 4,7-di(hydroxyimino)-4,7-dihydrobenzo-2,1,3-thiadiazole.

Keywords

Oxidation Sodium Potassium Organic Chemistry Acid Medium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • I. A. Belen'kaya
    • 1
  • N. S. Tsepova
    • 1
  • Ya. L. Kostyukovskii
    • 1
  • V. G. Pesin
    • 1
  1. 1.S. M. Kirov Academy of Military MedicineLeningrad

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