Skip to main content
Log in

Synthesis of substituted tetrahydro-1,3-oxazines

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A number of mono-, di-, tri-, and tetrasubstituted tetrahydro-1,3-oxazines were synthesized by the reaction of 3-amino- and 3-methylamino-1-propanols with aldehydes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature cited

  1. Z. Eckstein and T. Urbansky, Adv. Heterocycl. Chem., 2, 311 (1963).

    Google Scholar 

  2. H. L. Fischer, US Patent No. 2,326,733 (1943); Chem. Abstr., 38, 894 (1944).

    Google Scholar 

  3. E. L. Eliel and R. O. Hutchins, J. Am. Chem. Soc., 91, 2703 (1969).

    Google Scholar 

  4. F. G. Riddel, Quart. Rev., 21, 364 (1967).

    Google Scholar 

  5. Yu. Yu. Samitov, Dokl. Akad. Nauk SSSR, 164, 347 (1965).

    Google Scholar 

  6. F. G. Riddel and J. M. Lehn, J. Chem. Soc. B, 1224 (1968).

  7. M. Kohn, Monatsh., 25, 817, 850 (1904).

    Google Scholar 

  8. C. Mannich and H. Wieder, Ber., 65, 385 (1932).

    Google Scholar 

  9. C. Mannich and K. Roth, Arch. Pharm., 274, 527 (1936).

    Google Scholar 

  10. E. M. Hancock, E. M. Hardy, D. Heyl, M. E. Write, and A. Cope, J. Am. Chem. Soc., 66, 1747 (1944).

    Google Scholar 

  11. G. A. R. Kon and J. J. Roberts, J. Chem. Soc., 978 (1950).

  12. B. V. Unkovskii and L. A. Ignatova, USSR Author's Certificate No. 193,481 (1967); Byul. Izobr., No. 7 (1967).

  13. L. A. Ignatova, Yu. E. Kazantsev, and B. V. Unkovskii, Zh. Organ. Khim., 5, 1792 (1969).

    Google Scholar 

  14. B. V. Unkovskii, G. P. Chernysh, Yu. E. Kazantsev, E. P. Badosov, and Z. I. Smolina, USSR Author's Certificate No. 236,457 (1968); Byul. Izobr., No. 7 (1969).

  15. B. V. Unkovskii, G. P. Chernysh, and K. I. Romanova, USSR Author's Certificate No. 191,516 (1966); Byul. Izobr., No. 4 (1967).

  16. D. R. Howton, J. Org. Chem., 10, 277 (1945).

    Google Scholar 

  17. A. L. Morrison and H. Rinderknecht, J. Chem. Soc., 1510 (1950).

  18. H. S. Mosher, M. B. Frankel, and M. Gregory, J. Am. Chem. Soc., 75, 5326 (1953).

    Google Scholar 

  19. G. Drefahl and H. H. Hörhold, Ber., 94, 1641 (1961).

    Google Scholar 

  20. H. Conroy, in: Advances in Organic Chemistry, Vol. 2, Wiley (1960).

  21. P. J. Chivers and T. A. Crabb, Tetrahedron, 26, 3389 (1970).

    Google Scholar 

  22. H. D. Hartough, J. J. Dickert, and S. L. Meisel, US Patent No. 2,647,117 (1953); Chem. Abstr., 48, 8265 (1954).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 467–471, April, 1973.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Boiko, I.P., Kazantsev, Y.E., Malina, Y.F. et al. Synthesis of substituted tetrahydro-1,3-oxazines. Chem Heterocycl Compd 9, 431–434 (1973). https://doi.org/10.1007/BF00471518

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00471518

Keywords

Navigation