Abstract
4-Acetyl-3-hydroxy-5-hydroxymethyl-2-methylpyridine 5-phosphate (IV) was synthesized by oxidation of 3-hydroxy-5-hydroxymethyl-4-(α-hydroxyethyl)-2-methylpyridine 5-phosphate (III) with chromic anhydride. Compound III was obtained by phosphorylation of 3-hydroxy-5-hydroxymethyl-4-(α-hydroxyethyl)-2-methylpyridine with polyphosphoric acid (PPA). The UV and PMR spectra of the synthesized compounds were studied.
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See [1] for communication XIV.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 499–503, April, 1971.
The authors sincerely thank Academician A. E. Braunshtein for his constant interest in this work, V. I. Ivanov and A. F. Vanin for their fruitful discussions, and K. F. Turchin and I. I. Chervin for kindly providing the possibility for obtaining the PMR spectra.
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Karpeiskii, M.Y., Padyukova, N.S. & Florent'ev, V.L. Vitamin B6 analogs. Chem Heterocycl Compd 7, 465–468 (1971). https://doi.org/10.1007/BF00471486
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DOI: https://doi.org/10.1007/BF00471486