Abstract
1,2,5-Trimetnyl- and 1-(γ-chlorocrotyl)-2,5-dimethyl-5-(β-cyanoethyl)-4-piperidones were synthesized and separated into individual isomers. The corresponding isomeric 5-(β-carboxyethyl)-4-piperidones were obtained by hydrolysis. The isomeric 1,2,5-trimethyl-3,5-bis(β-cyanoethyl)- and 1,2,5-trimethyl-3,3,5-tris(β-cyanoethyl)-4-piperidones were synthesized by subsequent cyanoethylation of the individual 1,2,5-trimethyl-5-(β-cyanoethyl)-4-piperidone isomers.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 479–481, April, 1971.
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Sharifkanov, A.S., Bushneva, N.A. & Tokmurzin, K.K. Cyanoethylation of some n-substituted 2,5-dimethyl-4-piperidones. Chem Heterocycl Compd 7, 447–450 (1971). https://doi.org/10.1007/BF00471482
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DOI: https://doi.org/10.1007/BF00471482