Abstract
Substituted thiazoles, 1,4-benzothiazines, imidazo[2,1-b]thiazoles, and imidazo[1,2-a]pyridines containing acylamide residues as substituents were obtained by reaction of ω-chloro-ω-acylaminoacetophenones with thioamides, o-aminothiophenol, 2-aminothiazole, and 2-aminopyridine. Some of these substances can be used for the synthesis of heterocyclic bases with an unsubstituted amino group.
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B. S. Drach, I. Yu. Dolgushina, and A. V. Kirsanov, Zh. Organ. Khim., 8, 1224 (1972).
B. S. Drach, I. Yu. Dolgushina, and A. V. Kirsanov, Zh. Organ. Khim., 9, 414 (1973).
D. Matthies, Arch. Pharm., 301, 867 (1968).
D. Matthies, Synthesis (1972), p. 380.
A. H. Cook, S. I. Heilbron, and A. L. Levy, J. Chem. Soc., 1594 (1947).
A. H. Cook, S. I. Heilbron, and A. L. Levy, J. Chem. Soc., 1598 (1947).
W. L. Mosby, Heterocyclic Systems with Bridgehead Nitrogen Atoms, Part 1, New York (1961), pp. 157, 460.
Yoshio Tashika and Yoshihiro Nitta, J. Pharm. Soc. Japan, 72, 1157 (1952); Chem. Abstr., 47, 6939 (1953).
D. Ben-Ishai and A. Berger, J. Org. Chem., 17, 1564 (1952).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 928–931, July, 1974.
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Drach, B.S., Dolgushina, I.Y. & Sinitsa, A.D. Some cyclization reactions of ω-chloro-ω-acylamidoacetophenones. Chem Heterocycl Compd 10, 810–812 (1974). https://doi.org/10.1007/BF00471360
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DOI: https://doi.org/10.1007/BF00471360