Abstract
The 4-nitro derivative is formed in the nitration of 3,5-diphenylisoxazole (I) in acetic anhydride. Mononitration of isoxazole I in concentrated H2SO4 gave 3-phenyl-5-(p-nitrophenyl)isoxazole, while polynitration gave a mixture of dinitro derivatives, among which 3- (m-nitro-phenyl)-5-(p-nitrophenyl)isoxazole was identified. The structures of the isolated products were established by means of the spectra, by reaction-chromatography methods, and gasliquid chromatography, as well as by a comparison with genuine samples of the two mononitro and four dinitro derivatives of isoxazole I.
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See [1] for communication XXVII.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 597–601, May, 1974.
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Sokolov, S.D., Egorova, T.N. & Yudintseva, I.M. Research in the isoxazole series. Chem Heterocycl Compd 10, 516–520 (1974). https://doi.org/10.1007/BF00471316
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DOI: https://doi.org/10.1007/BF00471316