Skip to main content
SpringerLink
Log in

Synthesis of aldehydes and nitriles in the 5-hydroxyindole series

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A preparative method for the synthesis of previously inaccessible 3-formyl-5-hydroxyindole derivatives by Vilsmeier formylation of 5-acetoxyindoles is proposed. 5-Hydroxyindole-3-carboxylic acid nitriles and their 4-dimethylamino-methyl derivatives were obtained from 3-formyl-5-hydroxyindoles through their oximes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature cited

  1. V. I. Shvedov, A. K. Chizhov, and A. N. Grinev, Khim. Geterotsikl. Soedin., 399 (1971).

  2. A. N. Grinev, V. I. Shvedov, A. K. Chizhov, and R. A. Zinov'eva, USSR Author's Certificate No. 436,820 (1972); Byul. Izobr., No. 27, 49 (1974).

  3. V. I. Shvedov, G. N. Kurilo, and A. N. Grinev, Khim. Geterotsikl. Soedin., 208 (1971).

  4. A. N. Grinev, V. I. Shvedov, E. K. Panisheva, N. S. Bogdanova, I. S. Nikolaeva, and G. N. Pershin, Khim.-Farmats. Zh., No. 9, 9 (1969).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, Moscow

    A. N. Grinev, V. I. Shvedov, A. K. Chizhov & T. F. Vlasova

Authors
  1. A. N. Grinev
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. I. Shvedov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. K. Chizhov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. T. F. Vlasova
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1250–1253, September, 1975.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Grinev, A.N., Shvedov, V.I., Chizhov, A.K. et al. Synthesis of aldehydes and nitriles in the 5-hydroxyindole series. Chem Heterocycl Compd 11, 1087–1090 (1975). https://doi.org/10.1007/BF00471301

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00471301

Keywords

Search

Navigation