Abstract
2-OxO-3,3-dihydroxy-4-bromohexahydroazepine was obtained by bromination of an enamine of α-oxocaprolactam and subsequent hydrolysis of the resulting bromoimmonium salt and by direct bromination of α-oxocaprolactam. The reaction of the product with thiourea, N-substituted o-aminothiophenols, aminouracils, and acetoacetic ester gave derivatives of thiazolo[4,5-c] azepine, azepino[4,3-b][1,4]benzothiazine, azepino [3,4-b]pyrrolo [2,3-d] pyrimidine, and furo[2,3-c] azepine.
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R. G. Glushkov and V. G. Granik, Usp. Khim., 38, 1989 (1969).
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See [1] for communication XXVIII.
Translated from Khimiya Geterotsiklicheskikh Soedlnenii, No. 3, pp. 374–378, March, 1978.
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Glushkov, R.G., Smirnova, V.G., Zasosova, I.M. et al. Research on lactams. Chem Heterocycl Compd 14, 306–310 (1978). https://doi.org/10.1007/BF00470565
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DOI: https://doi.org/10.1007/BF00470565