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The synthesis of N-substituted 5-aminofurfurals

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A simple method for the synthesis of N-substituted 5-aminofurfurals based on the reaction of 5-halogenofurfurals with secondary amines has been developed. The reaction takes place through the formation of quaternary salts of N-substituted 5-aminofurfurals. 5-(Diethylamino)-, 5-(N-methyl-N-phenylamino)-, and 5-piperidinofurfurals have been obtained for the first time.

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References

  1. Z. N. Nazarova, V. N. Novikov, and V. S. Pustovarov, ZhOrKh, 2, 162, 1966.

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  2. K. Nakanishi, Absorption Spectroscopy, Practical [Russian translation], Moscow, 1965.

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Nazarova, Z.N., Pustovarov, V.S. The synthesis of N-substituted 5-aminofurfurals. Chem Heterocycl Compd 5, 434–436 (1969). https://doi.org/10.1007/BF00470248

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  • DOI: https://doi.org/10.1007/BF00470248

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