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Synthesis of 1-phenyl-3-methyl-4-alkyl-4-[N-methylbutyro(capro)lactyl]-5-pyrazolones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The corresponding hydrazones, which on heating are cyclized to give 1-phenyl-3-methyl-4-alkyl-(benzyl)-4-(2-oxopyrrolidinomethyl)- and 1-phenyl-3-methyl-4-alkyl(benzyl)-4-(N-methylcaprolactyl)pyrazolones, are formed in the reaction of alkyl(benzyl) (2-oxopyrrolidinomethyl)- and alkyl-(benzyl) (N-methylcaprolactyl)acetoacetic esters with phenylhydrazine.

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Literature cited

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1546–1548, November, 1976.

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Mesropyan, É.G., Bunyatyan, Y.A., Ambartsumyan, G.B. et al. Synthesis of 1-phenyl-3-methyl-4-alkyl-4-[N-methylbutyro(capro)lactyl]-5-pyrazolones. Chem Heterocycl Compd 12, 1272–1274 (1976). https://doi.org/10.1007/BF00470230

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  • DOI: https://doi.org/10.1007/BF00470230

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