Skip to main content
Log in

Indole derivatives

CIX. 5-(3-indolyl)-4-amino-6-hydroxypyrimidines

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

1-Carbomethoxy-3-indolylcyanoacetic ester reacts with amidines, guanidine, and thiourea to give, respectively, 2-alkyl- and 2-aryl-5-(3-indolyl)-4-amino-6-hydroxypyrimidines and 2-amino- and 2-thio-5-(3-indolyl)-4-amino-6-hydroxypyrimidines.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature cited

  1. N. N. Suvorov, V. S. Belezheva, A. V. Yarosh, Yu. V. Erofeev, and T. N. Kozik, Khim. Geterotsikl. Soedin., No. 8, 1099 (1975).

    Google Scholar 

  2. G. I. Zhungietu and G. N. Dorofeenko, Usp. Khim., 41, 1627 (1972).

    Google Scholar 

  3. R. Neidlein and G. Menche, Arch. Pharm., 305, 717 (1972).

    Google Scholar 

  4. D. J. Brown, The Pyrimidines, Wiley, New York-London (1962), p. 67.

    Google Scholar 

  5. V. S. Rozhkov, Yu. I. Smushkevich, T. A. Kozik, and N. N. Suvorov, Khim. Geterotsikl. Soedin., No. 11, 1502 (1974).

    Google Scholar 

  6. C. Jardetzky and O. Jardetzky, J. Amer. Chem. Soc., 82, 222 (1960).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

See [1] for communication CVIII.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1513–1515, November, 1976.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rozhkov, V.S., Smushkevich, Y.I. & Suvorov, N.N. Indole derivatives. Chem Heterocycl Compd 12, 1246–1248 (1976). https://doi.org/10.1007/BF00470224

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00470224

Keywords

Navigation