Abstract
2-Aryl-4H-3, 1-benzoxazin-4-ones were subjected to alkaline hydrolysis in O18-enriched water. It was established on the basis of data from mass-spectrometric analysis of the hydrolysis products that the C-2 and C-4 atoms of the benzooxazinone ring undergo nucleophilic attack. The primary direction of attack depends on the nature and position of the substituent.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 641–644, May, 1976.
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Bolotin, B.M., Poponova, R.V., Zeryukina, L.S. et al. Hydrolysis of 2-aryl-4h-3, 1-benzoxazin-4-ones. Chem Heterocycl Compd 12, 538–541 (1976). https://doi.org/10.1007/BF00470107
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DOI: https://doi.org/10.1007/BF00470107