Abstract
A general scheme is proposed for the synthesis of 4-alkylthiacyclohexanes by reaction of 1-alken-3-ylmagnesium halides with ethylene episulfide and subsequent cyclization of the resulting 3-alkylpent-4-ene-1-thiols under the in-fluence of UV irradiation. 4-Amyl- and 4-octylthiacyclohexanes, together with 2-methyl-3-octylthiacyclopentane, were obtained, respectively, from 1-octen-3-ylmagnesium bromide, 1-undecen-3-ylmagnesium chloride, and ethylene episulfide.
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See [1] for communication. VII.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1622–1624, December, 1977.
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Krivonogov, V.P., Dronov, V.I. & Nigmatullina, R.F. Synthesis of cyclic sulfides. Chem Heterocycl Compd 13, 1293–1296 (1977). https://doi.org/10.1007/BF00469886
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DOI: https://doi.org/10.1007/BF00469886