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Circumscribed lytic lesions of the thalassaemic skull

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Abstract

Solitary or multiple circumscribed osteolytic areas are described in seven patients, selected from 250 patients with homozygous β-thalassaemia (Cooley's anaemia). On X-ray examinations, these areas appear as purely osteolytic lesions with well-defined margins not associated with sclerosis. The possible mechanisms are discussed.

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Orzincolo, C., Castaldi, G., Bariani, L. et al. Circumscribed lytic lesions of the thalassaemic skull. Skeletal Radiol 17, 344–347 (1988). https://doi.org/10.1007/BF00367180

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