Summary
Shadowed electron micrographs show many details of the fine structure of threadlike bodies isolated from tortoise erythrocyte nuclei (comp. table 1). We consider it more appropriate to use the term “metabolic chromosome” to describe the threadlike bodies.
Assuming that the genes are found in the chromosome as morphological genetic units the nodules observed in the chromofilaments or a fraction of them presumably correspond to the genes.
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Literature cited
Calvet, F., B. Siegel and K. G. Stern: Electron optical observations on chromosome structure in resting cells. Nature (Lond.) 162, 305 (1948).
Claude, A., and J. S. Potter: Isolation of chromatin threads from the resting nucleus of leucemic cells. J. of exper. Med. 77, 345 (1943).
Gowen, J. W., and E. H. Gay: Gene number, kind and size in Drosophila. Genetics 18, 1 (1933).
Hovanitz, W.: An electron microscope study of isolated chromosomes. Genetics 32, 500 (1947).
Hovanitz, W., A. R. T. Denues and R. M. Sturrock: The internal structure of isolated chromosomes. Wasmann Collector 7, 233 (1949).
Lame, W. G. P.: Chromatin threads from cell nuclei. Nature (Lond.) 164, 109 (1949).
Mirsky, A. E., and H. Ris: Isolated chromosomes. J. gen. Physiol. 7, 1 (1947).
Mirsky, A. E., and H. Ris: The chemical composition of isolated chromosomes. J. gen. Physiol. 7, 7 (1947).
Muller, H. J.: On the dimensions of chromosomes and genes in the dipteran salivary glands. Amer. Naturalist 69, 378 (1935).
Pollister, A. W., and A. E. Mirsky: The isolation of chromosomes from resting nuclei. Genetics 28, 86 (1943).
Yasuzumi, G.: The micro-structure of chromatin threads in the metabolic stage of the nucleus. Chromosoma 4, 222 (1951).
Yasuzumi, G., Y. Mizuta and Y. Hasegawa: Electron microscopy of chromosomes. Jap. J. Genet. 25, 45 (1950).
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Yasuzumi, G., Miyao, G., Yamamoto, Y. et al. The microstructure and origin of the threadlike bodies isolated from the metabolic nucleus. Chromosoma 4, 359–368 (1950). https://doi.org/10.1007/BF00325779
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DOI: https://doi.org/10.1007/BF00325779