Abstract
Surgical excision followed by radiotherapy has been reported to be successful in the treatment of spinal cord compressions due to extramedullary hematopoiesis in patients affected by thalassemia. The authors report a case of cauda equina compression in such a patient successfully treated with repeated blood transfusions.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Abbassioun K, Amir-Jamshidi A (1982) Curable paraplegia due to extradural hematopoietic tissue in thalassemia. Neurosurgery 11:804–807
Cardia E, Toscano S, La Rosa G, et al (1991) Compressione midollare da tessuto emopoietico iperplastico in paziente con talassemia intermedia (abstract). XL Congresso Nazionale Società Italiana di Neurochirurgia, Perugia, 11–14 September 1991
Cauthen JC, McLaurin LP, Foster MT, et al (1968) Spinal cord compression secondary to extramedullary hematopoiesis in two brothers. Report of two cases. J Neurosurg 29:529–531
Cross JN, Morgan OS, Gibbs WN, et al (1977) Spinal cord compression in thalassemia. J Neurol Neurosurg Psychiatry 40:1120–1122
David CV, Balasubramanian P (1983) Paraplegia with thalassemia. Aust NZ J Surg 53:283–284
Gatto I, Terrana V, Biondi L (1954) Compressione sul midollo spinale da proliferazione di midollo osseo nello spazio epidurale in soggetto affetto da malattia di Cooley splenectomizzato. Haematologica 38:61–75
Heffner RR Jr, Koehl RH (1970) Hematopoiesis in the spinal epidural space. Case report. J Neurosurg 32:485–490
Knoblich R (1960) Extramedullary hematopoiesis presenting as intrathoracic tumors. Cancer 13:462–468
Lowman RM, Bloor CM, Newcomb AW (1963) Roentgen manifestations of thoracic extramedullary hematopoiesis. Dis Chest 44:154–162
Luitjes WF, Braakman R, Abels J (1982) Spinal cord compression in a new homozygous variant of β-thalassemia. Case report. J Neurosurg 57:846–848
Luyendijk W, Went L, Schaad HDG (1975) Spinal cord compression due to extramedullary hematopoiesis in homozygous thalassemia. Case report. J Neurosurg 42:212–216
Lyall A (1935) Massive extramedullary bone marrow formation in a case of pernicious ancemia. J Pathol Bacteriol 41:469–472
Mann KS, Yue CP, Chan KH, et al (1987) Paraplegia due to extramedullary hematopoiesis in thalassemia. J Neurosurg 66:938–940
Marinozzi V (1958) Aspetti insoliti dell'iperplasia midollare nelle anemie emolitiche. I. Masse midollari neoplastiformi intratoraciche in un uomo con thalassemia minor. II. Invasione midollare dello spazio epidurale in una bambina con morbo di Cooley. Haematologica 43:737–759
Mihindukulasuriya JCL, Chanmugam D, Machado V, et al (1977) A case of paraparesis due to extramedullary hematopoiesis in HbE-thalassemia. Postgrad Med J 53:393–397
Prabhakar S, Chopra JS, Khosla VK, et al (1980) Spinal cord compression in homozygous beta-thalassemia. Surg Neurol 13:351–354
Sorsdahl OS, Taylor PE, Noyes WD (1964) Extramedullary hematopoiesis, mediastinal masses and spinal cord compression. JAMA 189:343–347
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Mancuso, P., Zingale, A., Basile, L. et al. Cauda equina compression syndrome in a patient affected by thalassemia intermedia: complete regression with blood transfusion therapy. Child's Nerv Syst 9, 440–441 (1993). https://doi.org/10.1007/BF00306203
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00306203