Smooth endoplasmic reticulum proliferation in mouse enterocytes induced by fructose feeding

Summary

Adult male mice receiving a fructose diet show, after three days, a large proliferation of the smooth endoplasmic reticulum in the jejunal absorptive cells. This extension is a secondary stage of the trememdous increase of the glucose-6-phosphatase activity and seems to result from a crypt regulation. Glucose feeding does not provoke the same morphologic changes.

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This work was supported by a research grant from the Medical Research Council of Canada.

Dr. D. Maestracci Ph. D. is a recipient of a Centennial Fellowship of the Medical Research Council of Canada.

Mr. D. Ménard is a recipient of a studentship of the Medical Reserach Council of Canada.

The authors are greatly indebted to Mrs. S. Sinave for her skillful technical assistance.

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Hugon, J.S., Maestracci, D. & Ménard, D. Smooth endoplasmic reticulum proliferation in mouse enterocytes induced by fructose feeding. Histochemie 29, 189–197 (1972). https://doi.org/10.1007/BF00306142

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Keywords

  • Public Health
  • Glucose
  • Endoplasmic Reticulum
  • Fructose
  • Morphologic Change