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Radioimmunoassays of Ethinyl-norgestrienone (R-2323) and medroxyprogesterone acetate (MPA) and their clinical applicability

Urological Research volume 5, pages 55–59 (1977)Cite this article

Summary

Radioimmunoassays for 2 synthetic progestins (Ethinyl-norgestrienone, R 2323 and medroxyprogesterone acetate, MPA) are demonstrated. 10 patients aged 31 to 72 years were treated with ethinyl-norgestrienone with different schedules and 3 men suffering from benign prostatic hypertrophy were treated with medroxyprogesterone acetate. Plasma levels of testosterone, LH, FSH were monitored before, during and after treatment.

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References

  1. Bartke, A., Steele, R. E., Musto, N., Caldwell, B. V.: Fluctuations in plasma testosterone levels in adult male rats and mice. Endocrinology 92, 1223 (1973)

    Google Scholar 

  2. Cornette, J. C. et al.: Measurement of medroxyprogesterone acetate (Provera) by radioimmunoassay. Journal of Clinical Endocrinology and Metabolism 33, 459 (1971)

    Google Scholar 

  3. Coyotupa, J., Parlow, A. F., Abraham, G. E.: Simultaneous radioimmunoassay of plasma testosterone and dihydrotestosterone. Anal Lett 5, 329 (1972)

    Google Scholar 

  4. Crosignani, P. G., Nakamura, R. M. Hovland, D. N., Mishell, D. R., Jr.: A method of solid phase radioimmunoassay utilizing polypropylene discs. Journal of Clinical Endocrinology and Metabolism 30, 153 (1970)

    Google Scholar 

  5. Edquist, L. E., Johansson, E. D.: Radioimmunoassay of oestrone and oestradiol in human and bovine peripheral plasma. Acta endocrinologica 71, 716 (1972)

    Google Scholar 

  6. Frick, J.: Control of spermatogenesis in men by combined administration of progestin and androgen. Contraception 8, 103 (1973)

    Google Scholar 

  7. Greenwood, F. C., Hunter, W. M., Glover, J. S.: The preparation of 131I-labelled human growth hormone of high specific radioactivity. Biochemical Journal 89, 114 (1963)

    Google Scholar 

  8. Johansson, E. D. B., Nygren, K. G.: Depression of plasma testosterone levels in men with norethindrone. Contraception 8, 219 (1973)

    Google Scholar 

  9. Kaiser, D. G., Carlson, R. G., Kirton, K. T.: GLC determination of medroxyprogesterone acetate in plasma. Journal of Pharmaceutical Sciences 63, 420 (1974)

    Google Scholar 

  10. Kirton, K. T., Cornette, J. C.: Return of ovulatory cyclicity following an intramuscular injection of medroxy-progesterone acetate (Provera). Contraception 10, 39 (1974)

    Google Scholar 

  11. Viinikka, L., Johansson, E. D. B., Jänne, O., Victor, A.: The release of a synthetic progestin, R-2323, from polysilastic vaginal rings. (Submitted for Publication)

  12. Zanartu, J., Pupkin, M., Rosenberg, D.: Long-term effect of medroxy-progesterone acetate in human ovarian morphology and sperm transport. Fertility and Sterility 21, 525 (1970)

    Google Scholar 

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Authors and Affiliations

  1. Department of Urology, University of Innsbruck, Innsbruck, Austria

    J. Frick, G. Bartsch & G. Jakse

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  1. J. Frick
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  2. G. Bartsch
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  3. G. Jakse
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Frick, J., Bartsch, G. & Jakse, G. Radioimmunoassays of Ethinyl-norgestrienone (R-2323) and medroxyprogesterone acetate (MPA) and their clinical applicability. Urol. Res. 5, 55–59 (1977). https://doi.org/10.1007/BF00256842

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  • DOI: https://doi.org/10.1007/BF00256842

Key words

  • Ethinyl-norgestrienone (R-2323)
  • Medroxyprogesterone acetate (MPA)
  • Radioimmunoassay