Study of neutron production and moderation for sulfur neutron capture therapy

  • Meng PengEmail author
  • Guo-Zhu He
  • Qi-Wei Zhang
  • Bin Shi
  • Hong-Qing Tang
  • Zu-Ying Zhou


Neutron capture therapy with Sulfur-33, similar to boron neutron capture therapy with Boron-10, is effective in treating some types of tumors including ocular melanoma. The key point in sulfur neutron capture therapy is whether the neutron beam flux and the resonance capture cross section of \(^{33}\hbox {S(n},\alpha )^{30}\hbox {Si}\) reaction at 13.5 keV can achieve the requirements of radiotherapy. In this research, the authors investigated the production of 13.5 keV neutron production and moderation based on an accelerator neutron source. A lithium glass detector was used to measure the neutron flux produced via near threshold \(^{7}\hbox {Li(p,n)}^{7}\hbox {Be}\) reaction using the time-of-flight method. Furthermore, the moderation effects of different kinds of materials were investigated using Monte Carlo simulation.


Sulfur Neutron capture therapy Boron neutron capture therapy \(^{33}\hbox {S(n}, \alpha )^{30}\hbox {Si}\) resonance reaction \({}^{7}\hbox {Li(p, n)}^{7}\hbox {Be}\) neutron source 


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Copyright information

© China Science Publishing & Media Ltd. (Science Press), Shanghai Institute of Applied Physics, the Chinese Academy of Sciences, Chinese Nuclear Society and Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Meng Peng
    • 1
    • 2
    Email author
  • Guo-Zhu He
    • 1
  • Qi-Wei Zhang
    • 1
  • Bin Shi
    • 1
  • Hong-Qing Tang
    • 1
  • Zu-Ying Zhou
    • 1
  1. 1.Key Laboratory of Nuclear DataChina Institute of Atomic EnergyBeijingChina
  2. 2.College of Liberal Arts and SciencesNational University of Defense TechnologyChangshaChina

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