Chitosan Nanoparticle for Loading and Release of Nitrogen, Potassium, and Phosphorus Nutrients

  • Negar Motakef KazemiEmail author
  • Ali Asghar Salimi
Research Paper
Part of the following topical collections:
  1. Chemistry


In the present study, chitosan nanoparticle (Ch NP) was prepared by polymerizing methacrylic acid for loading of nitrogen (N), potassium (K), and phosphorus (P) nutrients as fertilizer. Nutrient loading was done by suspensions of Ch nanoparticles with urea, calcium phosphate, and potassium chloride as sources of N, P, and K, respectively. The products were characterized by dynamic light scattering for determination of size and size distribution, zeta potential for signification of surface charge, scanning electron microscopy for investigation of size and morphology, Fourier transform infrared spectrum for characterization of functional group, UV–Vis spectroscopy for phosphorus loading, atomic adsorption spectroscopy for potassium loading, and KJDAL digestion method for nitrogen loading. The amount of nutrient release was investigated after 168 h in water solution at room temperature. According to the results, nutrient loading caused the increase in the size and the decrease in the stability due to loaded components. However, the percentage of nutrient loading differs not so much, but the percentage of nutrient release differs. Based on the obtained results, Ch NP is a good candidate as fertilizer for agricultural applications.


Chitosan Nanoparticle Nitrogen Potash Phosphorus 


  1. Calabria L, Vieceli N, Bianchi O, de Oliveira RVB, do Nascimento Filho I, Schmidt V (2012) Soy protein isolate/poly (lactic acid) injection-molded biodegradable blends for slow release of fertilizers. Ind Crops Prod 36:41–46CrossRefGoogle Scholar
  2. Coma V, Martial-Gros A, Garreau S, Copinet A, Salin F, Deschamps A (2002) Edible antimicrobial films based on chitosan matrix. J Food Sci 67:1162–1169CrossRefGoogle Scholar
  3. Corradini E, de Moura MR, Mattoso LHC (2010) A preliminary study of the incorporation of NPK fertilizer into chitosan nanoparticles. Express Polym Lett 4(8):509–515CrossRefGoogle Scholar
  4. DeRosa MC, Monreal C, Schnitzer MR, Walsh R, Sultan Y (2010) Nanotechnology in fertilizers. Nat Nanotechnol 5:91CrossRefGoogle Scholar
  5. Ghormade V, Deshpande MV, Paknikar KM (2011) Perspectives for nano-biotechnology enabled protection and nutrition of plants. Biotechnol Adv 29:792–803CrossRefGoogle Scholar
  6. González-Melendi P, Fernández-Pacheco R, Coronado MJ, Corredor E, Testillano PS, Risueño MC, Marquina C, Ibarra MR, Rubiales D, Pérez-de-Luque A (2008) Nanoparticles as smart treatment-delivery systems in plants: assessment of different techniques of microscopy for their visualization in plant tissues. Ann Bot 101(1):187–195CrossRefGoogle Scholar
  7. Goy RC, Morais STB, Assis OBG (2016) Evaluation of the antimicrobial activity of chitosan and its quaternized derivative on E. coli and S. aureus growth. Braz J Pharmacogn 26:122–127CrossRefGoogle Scholar
  8. Guo MY, Liu MZ, Zhan FL, Wu L (2005) Preparation and properties of a slow-release membrane-encapsulated urea fertilizer with superabsorbent and moisture preservation. Ind Eng Chem Res 44:4206–4211CrossRefGoogle Scholar
  9. Hadwiger LA (2013) Multiple effects of chitosan on plant systems: solid science or hype. Plant Sci 208:42–49CrossRefGoogle Scholar
  10. Jin S, Yue G, Feng L, Han Y, Yu X, Zhang Z (2011) Preparation and properties of a coated slow-release and water-retention biuret phosphoramide fertilizer with superabsorbent. J Agric Food Chem 59:322–327CrossRefGoogle Scholar
  11. Li Q, Dunn ET, Grandmaison EW (1992) Applications and properties of chitosan. J Bioact Compat Polym 7(4):370–397CrossRefGoogle Scholar
  12. Liu R, Lal R (2015) Potentials of engineered nanoparticles as fertilizers for increasing agronomic productions. Sci Total Environ 514:131–139CrossRefGoogle Scholar
  13. Luque-Alcaraz AG, Lizardi-Mendoza J, Goycoolea FM, Higuera-Ciapara I, Arguelles-Monal W (2016) Preparation of chitosan nanoparticles by nanoprecipitation and their ability as a drug nanocarrier. RSC Adv 6:59250–59256CrossRefGoogle Scholar
  14. Mandal KG, Hati KM, Misra AK (2009) Biomass yield and energy analysis of soybean production in relation to fertilizer-NPK and organic manure. Biomass Bioenergy 33:1670–1679CrossRefGoogle Scholar
  15. Mincea M, Negrulescu A, Ostafe V (2012) Preparation, modification, and applications of chitin nanowhiskers: a review. Rev Adv Mater Sci 30:225–242Google Scholar
  16. Mohammed MA, Syeda JTM, Wasan KM, Wasan EK (2017) An overview of chitosan nanoparticles and its application in non-parenteral drug delivery. Pharmaceutics 9:53–79CrossRefGoogle Scholar
  17. Naderi MR, Danesh-Shahraki A (2013) Nanofertilizers and their roles in sustainable agriculture. Int J Agric Crop Sci 5:2229–2232Google Scholar
  18. Ni B, Liu M, Lu S, Xie L, Wang Y (2010) Multifunctional slow-release organic–inorganic compound fertilizer. J Agric Food Chem 58:12373–12378CrossRefGoogle Scholar
  19. No HK, Meyers SP, Prinyawiwatkul W, Xu Z (2007) Applications of chitosan for improvement of quality and shelf life of foods: a review. J Food Sci 72:87–100CrossRefGoogle Scholar
  20. Pellá MCG, Lima-Tenório MK, Tenório-Neto ET, Guilherme MR, Muniz EC, Rubira AF (2018) Chitosan-based hydrogels: from preparation to biomedical applications. Carbohydr Polym 196:233–245CrossRefGoogle Scholar
  21. Qi L, Xu X, Jiang X, Hu C, Zou X (2004) Preparation and antibacterial activity of chitosan nanoparticles. Carbohydr Res 339:2693–2700CrossRefGoogle Scholar
  22. Silalahi J, Situmorang P, Patilaya P, Silalahi YCE (2016) Antibacterial activity of chitosan and hydrolyzed coconut oil and their combination against Bacillus cereus and Escherichia coli. Asian J Pharm Clin Res 9(5):69–73CrossRefGoogle Scholar
  23. Smith JD, Harrison HC (1991) Evaluation of polymers for controlled-release properties when incorporated with nitrogen fertilizer solutions. Commun Soil Sci Plant Anal 22(5–6):559–573CrossRefGoogle Scholar
  24. Teodorescu M, Lungu A, Stanescu PO, Neamtu C (2009) Preparation and properties of novel slow-release NPK agrochemical formulations based on poly (acrylic acid) hydrogels and liquid fertilizers. Ind Eng Chem Res 48:6527–6534CrossRefGoogle Scholar
  25. Wilson MA, Tran NH, Milev AS, Kannangara GSK, Volk H, Lu GHM (2008) Nanomaterials in soils. Geoderma 146:291–302CrossRefGoogle Scholar
  26. Wu L, Liu M (2008) Preparation and properties of chitosan-coated NPK compound fertilizer with controlled-release and water-retention. Carbohydr Polym 72:240–247CrossRefGoogle Scholar
  27. Wu L, Liu M, Rui L (2008) Preparation and properties of a double-coated slow-release NPK compound fertilizer with superabsorbent and water-retention. Bioresour Technol 99:547–554CrossRefGoogle Scholar
  28. Zhao G, Liu Y, Tian Y, Sun Y, Cao Y (2010) Preparation and properties of macromelecular slow-release fertilizer containing nitrogen, phosphorus and potassium. J Polym Res 17:119–125CrossRefGoogle Scholar

Copyright information

© Shiraz University 2019

Authors and Affiliations

  1. 1.Department of Medical Nanotechnology, Faculty of Advanced Sciences and Technology, Tehran Medical SciencesIslamic Azad UniversityTehranIran
  2. 2.Department of Nano Chemistry, Faculty of Pharmaceutical Chemistry, Tehran Medical SciencesIslamic Azad UniversityTehranIran

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