Ovarian cancer is one of the common gynecological cancers with high mortality rates. The study was conducted to know prevalence, histopathological variants, presentation and outcome in women with ovarian tumors.
Present study was conducted in Obstetrics and Gynecology department of rural tertiary center over one year (December 2017–November 2018) on women with unilateral/bilateral ovarian masses fulfilling inclusion criteria. Demographic features including age, parity, nature, laterality and histopathological variants were analyzed and compared. Statistical analysis was done using SPSS 20.0 version software.
Of 122 cases, 49 (40.2%) had benign tumors, 05 (4.1%) borderline, 64 (52.5%) primary malignant tumors and 04 (3.3%) secondary metastatic deposits. Majority of the women (60.3%) with malignant tumors presented at stage II/III. Most of the women (89.8%) with benign tumors had unilateral lesions, and 64.1% women with malignant tumors had bilateral masses (p < 0.05). Both benign (59.1%) and malignant (87.0%) unilateral ovarian masses were more common on right. CA125 was significantly higher in women with malignant tumors as compared to benign (p = 0.024) and borderline tumors (p = 0.386). On histopathological examination, most common malignant ovarian tumor was serous cystadenocarcinoma (39.1%) and in benign mature teratomas (42.9%). Diabetes mellitus was significantly associated with malignant ovarian tumors (p = 0.016).
Epithelial ovarian tumors were most common malignant tumors and mature teratomas most common benign tumors. Ovarian malignancies present at advanced stage and have high mortality.
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I thank Dr. Namit Kant Singh for his advice and constant support.
This study did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors.
Conflict of interest
The authors declare that they have no conflict of interest.
All procedures performed in the present study involving human participants were in accordance with the ethical standards of the MMIMSR research ethical committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
The present study was conducted after proper informed written consent from the participants in their own language.
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Kumar, N., Yadav, A. & Kaur, H. Histopathological Variants of Ovarian Tumors and Their Presentation in Rural Tertiary Care Center of Northern India: An Observational Study. Indian J Gynecol Oncolog 18, 22 (2020) doi:10.1007/s40944-020-0370-6
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