Primitive Neuroectodermal Tumor (PNET) of the Endometrium
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Primitive neuroectodermal tumor (PNET) is a rare and highly aggressive neoplasm that originates in neural crest neuroectodermal cells. It presents a bimodal distribution, which can affect both young and postmenopausal women. About 30% of patients present metastatic disease at the moment of diagnosis, and their survival in 2 years ranges from 25 to 60%. In this report, we describe the case of a 42-year-old patient with a history of vaginal bleeding and a growing tumor compromising the endometrium, initially diagnosed as an endometrial adenocarcinoma, which immunohistochemistry posteriorly revealed a PNET of the endometrium. She was treated with neoadjuvant chemotherapy but had an unfortunate evolution and died.
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Conflict of interest
The authors declare that they have no conflict of interest.
Informed consent was obtained from the patient whose case was reported in this manuscript.
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