Elevated Ovarian Germ Cell Tumour Markers in a Case of Disseminated Tuberculosis
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India has the highest burden of both pulmonary and extrapulmonary tuberculosis (TB). Chronic untreated case of tuberculosis may spread to other abdominal structures causing disseminated TB often mimicking signs and symptoms of abdominal malignancy. We present a case of ovarian tumour with high ovarian germ cell tumour marker levels, but the final diagnosis was disseminated tuberculosis. Patient responded well to antitubercular therapy, and serum CA125, LDH, AFP and beta-HCG became normal. In our case, elevation of tumour markers was considered as a reflection of disseminated TB, so tumour markers were normal at the end of antitubercular treatment.
KeywordsTuberculosis mimics ovarian cancer Raised germ cell markers in disseminated tuberculosis Unusual presentation of disseminated TB HCG and TB AFP and TB
World Health Organization
Acquired immunodeficiency syndrome
- CA 125
Cancer antigen 125
Beta-human chorionic gonadotropin
Computerised abdominal tomography
Human immunodeficiency virus
Hepatitis B surface antigen
- ZN stain
Compliance with Ethical Standards
Conflict of interest
The authors declare that they have no conflict of interest.
Research involving Human Participants and/or Animals
The patient received standard of care treatment.
Informed consent from the patient was obtained before preparing the manuscript.
- 1.Global Tuberculosis Report, World Health organisation, 20th Edition. 2015. http://www.who.int/tb/publications/global_report/gtbr15_main_text.pdf. Accessed 30 Aug 2018.
- 2.Abi-Fadel F, Gupta K. Acute respiratory distress syndrome with miliary tuberculosis: a fatal combination. J Thorac Dis. 2013;5(1):E1–4. https://doi.org/10.3978/j.issn.2072-1439.2012.07.02.CrossRefPubMedPubMedCentralGoogle Scholar
- 5.Rakha S, Bayliss C, Sanderson F, Smith R, Seckl M, Savage P. Pituitary hCG production and cerebral tuberculosis mimicking disease progression during chemotherapy for an advanced ovarian germ cell tumour. BMC Cancer. 2010;10:338. https://doi.org/10.1186/1471-2407-10-338.CrossRefPubMedPubMedCentralGoogle Scholar