Postmenopausal Woman with Ovarian Yolk Sac Tumor and Associated Mucinous Carcinoma: A Case Report and Review of Literature
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Germ cell tumors account for 2–3% of ovarian malignancies. They typically occur in young females and have been rarely documented in postmenopausal women. Their rarity in postmenopausal women along with the histologic variability of yolk sac tumors, sometimes mimicking somatic malignancies, may pose a diagnostic challenge. We report a case of ovarian yolk sac tumor with associated mucinous carcinoma in a postmenopausal woman. They have been reported to behave aggressively and are less responsive to chemotherapy.
KeywordsYolk sac tumor Mucinous Adenocarcinoma Postmenopausal
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Conflict of interest
The authors declare that they have no conflict of interest.
- 7.Miettinen M, Wang Z, McCue PA, Sarlomo-Rikala M, Rys J, Biernat W, Lasota J, Lee YS. SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. Am J Surg Pathol. 2014;38(3):410–20. https://doi.org/10.1097/PAS.0000000000000116.CrossRefPubMedPubMedCentralGoogle Scholar
- 8.Nogales FF, Quiñonez E, López-Marín L, Dulcey I, Preda O. A diagnostic immunohistochemical panel for yolk sac (primitive endodermal) tumours based on an immunohistochemical comparison with the human yolk sac. Histopathology. 2014;65(1):51–9. https://doi.org/10.1111/his.12373.CrossRefPubMedGoogle Scholar