An Aggressive Case of Carcinoma of Cervix with Ovarian Metastasis
With an estimated 570,000 cases and 311,000 deaths in 2018 worldwide, cervical cancer is ranked as the fourth most frequently diagnosed cancer and the fourth leading cause of cancer death in women . Cervical cancer ranks second in incidence and mortality behind breast cancer, and the performance of inadequate hysterectomy is not uncommon owing to the lack of proper investigative evaluations and/or a lack of expertise in primary care hospitals. The ideal treatment for salvage in this setting is radical parametrectomy with lymph node dissection or radical radiotheraphy. Since it may be technically difficult to perform an adequate radical surgery after a previous hysterectomy, definitive post-operative irradiation is usually advocated. Improved survival rates were reported after adjuvant radiotherapy in patients with no gross residual disease after hysterectomy; however, poor survival has been reported after adjuvant radiotherapy in patients with confirmed gross residual...
Compliance with ethical standards
Conflict of interest
The authors declare that there are no conflicts of interest.
- 3.International Agency for Research on Cancer (IARC). IARC handbooks of cancer prevention: volume 10-cervix cancer screening. Lyon: IARC Press; 2005. iarc.fr/en/publications/pdfs-online/prev/handbook10/HANDBOOK10.pdf. Accessed 21 June 2018.
- 4.Singleton HM, Orr JW. Primary surgical treatment of invasive cancer. In: Singleton HM, Orr JW, editors. Cancer of the cervix. Philadelphia: JB Lippincott Company; 1995. p. 174.Google Scholar
- 7.Elishaev E, Gilks CB, Miller D, et al. Synchronous and metachronous endocervical and ovarian neoplasms: evidence supporting interpretation of the ovarian neoplasms as metastatic endocervical adenocarcinomas simulating primary ovarian surface epithelial neoplasms. Am J Surg Pathol. 2005;29:281–94.CrossRefGoogle Scholar
- 8.Carcangiu ML, Chambers JT, Voynick IM, et al. Immunohistochemical evaluation of estrogen and progesterone receptor content in 183 patients with endometrial carcinoma. Part I: clinical and histologic correlations. Am J Clin Pathol. 1990;94(247):254.Google Scholar