Pathological Complete Response (PCR) with TDM1 (Trastuzumab Emtansine) in Refractory HER2-Positive Locally Advanced Breast Cancer (LABC)

  • Manikandan DhanushkodiEmail author
  • Priya Iyer
  • Balasubramanian Ananthi
  • Arvind Krishnamurthy
Case report


We report a patient with HER2-positive locally advanced breast cancer who progressed on neoadjuvant chemotherapy, chemoradiation and anti-HER2-based chemotherapy but achieved complete pathologic response with TDM1 (trastuzumab emtansine).


TDM1 Pathologic complete response 


Compliance with Ethical Standards

Conflict of interest

Authors declare that they have no conflict of interest.


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Copyright information

© Association of Gynecologic Oncologists of India 2019

Authors and Affiliations

  1. 1.Department of Medical OncologyCancer Institute (WIA)ChennaiIndia
  2. 2.Department of Radiation OncologyCancer Institute (WIA)ChennaiIndia
  3. 3.Department of Surgical OncologyCancer Institute (WIA)ChennaiIndia

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