Pseudo-Meigs’ Syndrome Caused by Recurrent Leiomyoma Uterus

  • Vijay Zutshi
  • Sana TiwariEmail author
  • Sakshi Sirswal
Case Report


Leiomyoma uterus is the most common cause for pseudo-Meigs’ syndrome. A huge abdominopelvic mass with massive ascites can be mistaken with ovarian neoplasm. Ultrasonography is the primary modality used for diagnosis. The cystic degenerations present in leiomyoma can mimic as ovarian tumor and pose a diagnostic dilemma. There is a risk of recurrence of leiomyoma after myomectomy, thereby subjecting the patient to repeat surgery. Raised levels of CA 125 can also mislead in making the diagnosis. Cases of pseudo-Meigs’ syndrome have good prognosis.


Recurrent leiomyoma Massive ascites Cystic degeneration 


Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interests.


  1. 1.
    Salmon U. Benign pelvic tumors associated with ascites and pleural effusion. J Mount Sinai Hosp N Y. 1934;1:169–74.Google Scholar
  2. 2.
    Amant F, Gabriel C, Timmerman D, Vergote I. Pseudo-Meigs’ syndrome caused by a hydropic degenerating uterine leiomyoma with elevated CA 125. Gynecol Oncol. 2001;83(1):153–7.CrossRefPubMedGoogle Scholar
  3. 3.
    Mostaghel N, Enzevaei A, Zare K, Fallahian M. Struma ovarii associated with Pseudo-Meig’s syndrome and high serum level of CA 125; a case report. J Ovarian Res. 2012;5:10.CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Jin C, Dong R, Bu H, Yuan M, Zhang Y, Kong B. Coexistence of benign struma ovarii, pseudo-Meigs’ syndrome and elevated serum CA 125: case report and review of the literature. Oncol Lett. 2015;9(4):1739–42.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Kumar D, Pandey V, Jasnardhan S, Datti NS. Broad ligament fibroid mimicking as ovarian tumor on ultrasonography and computed tomography scan. J Clin Imaging Sci. 2013;3(8):3.PubMedGoogle Scholar
  6. 6.
    Murase E, Siegelman ES, Outwater EK, Perez-Jaffe LA, Tureck RW. Uterine leiomyomas: histopathologic features, MR imaging findings, differential diagnosis and treatment. Radiographics. 1999;19(5):1179–97.CrossRefPubMedGoogle Scholar
  7. 7.
    Bonney V. The technique and results of myomectomy. Lancet. 1931;220:171–3.CrossRefGoogle Scholar
  8. 8.
    Fauconnier A, Chapron C, Babaki-Fard K, Dubuisson JB. Recurrence of leiomyomata after myomectomy. Hum Reprod Update. 2000;6:595–602.CrossRefPubMedGoogle Scholar
  9. 9.
    Abramov Y, Anteby SO, Fasouliotis SJ, Barak V. The role of inflammatory cytokines in Meigs’ syndrome. Obstet Gynecol. 2002;99(5):917–9.PubMedGoogle Scholar
  10. 10.
    Weise M, Westphalen S, Fayyazi A, Emons G, Krauss T. Pseudo-Meigs syndrome: uterine leiomyoma with bladder attachment associated with ascites and hydrothorax—a rare case of a rare syndrome. Onkologie. 2002;25(5):443–6.PubMedGoogle Scholar

Copyright information

© Association of Gynecologic Oncologists of India 2018

Authors and Affiliations

  1. 1.Department of Obstetrics and GynaecologyVMMC and Safdarjung HospitalNew DelhiIndia
  2. 2.Department of PathologyVMMC and Safdarjung HospitalNew DelhiIndia

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