Angiosarcoma of Breast in Pregnancy: A Rare Case Report

  • Chandrakala MagudapathiEmail author
  • Haritha Garreepally
  • Arulraj Pichamuthu
  • Rajkumar Arumugam
  • Radha Ananthakrishnan
Case Report


Angiosarcoma of the breast is a rare aggressive malignancy of the endothelial origin with a tendency for local regional recurrence. A frequent clinical presentation is a painful palpable smooth mass or diffuse enlargement of the breast without a palpable mass but with purple discoloration of the overlying skin with apparent bruising. The aim is to give optimal treatment to the mother to maximize the chances of survival, while minimizing the risk of harm of the fetus. Here, we present a rare case of angiosarcoma of breast during pregnancy. Twenty-seven-year-old primigravida at 25 weeks of gestation presented to our hospital with complaints of lump in right breast with rapid increase in size and associated with pain. Ultrasound-guided FNAC showed features of angiosarcoma; hence, right-sided modified radical mastectomy was performed. Histopathological findings and epithelial markers of the removed tumor confirmed as angiosarcoma with no evidence of lymph node involvement. HRCT lungs showed metastasis in right lung middle lobe. In view of metastasis, she was treated with adjuvant chemotherapy before and after delivery.


Angiosarcoma Breast Pregnancy 


Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Association of Gynecologic Oncologists of India 2018

Authors and Affiliations

  1. 1.Department of Obstetrics and GynaecologyGenesis Royal InfirmaryCoimbatoreIndia
  2. 2.Department of Obstetrics and GynaecologyG. Kuppuswamy Naidu Memorial HospitalCoimbatoreIndia
  3. 3.Department of OncologyG. Kuppuswamy Naidu Memorial HospitalCoimbatoreIndia
  4. 4.Department of PathologyG. Kuppuswamy Naidu Memorial HospitalCoimbatoreIndia

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