Journal of Medical and Biological Engineering

, Volume 39, Issue 4, pp 490–497 | Cite as

Complexity-Based Analysis of the Difference Between Normal Subjects and Subjects with Stuttering in Speech Evoked Auditory Brainstem Response

  • Marjan MozaffarileghaEmail author
  • Hamidreza Namazi
  • Ali Akbar Tahaei
  • Sajad Jafari
Original Article


Deficits in auditory processing are an assumed underlying mechanism in stuttering. Previous studies have demonstrated that speech evoked auditory brainstem response (s-ABR) is a reliable method to evaluate brainstem timing in clinical populations with persistent developmental stuttering (PDS). The examination of s-ABR signals to quantify differential complexities between PDS and normal subjects using linear analysis is unreliable. This prompted us to evaluate non-linear methods, which are more effective for conveying complex dynamics. The aim of the current study is to apply fractal dimension and the Hurst exponent to s-ABR signals in order to identify complexity differences between PDS and normal subjects who were stimulated with the synthetic/da/stimulus. Analysis of scaling exponents showed a statistically significant difference between the two groups. The s-ABR signal in subjects with stuttering becomes more complex due to stimulation. These findings are discussed in terms of dysfunctional sub-cortical activation in PDS populations.


Speech evoked auditory brainstem response (s-ABR) Persistent developmental stuttering (PDS) Fractal dimension Hurst exponent Complexity 


Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures in studies involving human participants were performed in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Taiwanese Society of Biomedical Engineering 2018

Authors and Affiliations

  1. 1.Department of Biomedical Engineering and Physics, School of MedicineShahid Beheshti University of Medical SciencesTehranIran
  2. 2.Biomedical Engineering DepartmentAmirkabir University of TechnologyTehranIran
  3. 3.Department of Audiology, School of Rehabilitation SciencesIran University of Medical SciencesTehranIran

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