Urinary symptoms: broadening the horizons for the copeptin assay

  • T. F. MonaghanEmail author
  • D. L. Bliwise
  • A. J. Wein



The authors thank Karel Everaert, Jason M. Lazar, Joseph G. Verbalis, and Jeffrey P. Weiss for their contributions to the content and critical revisions of this correspondence.

Author contributions

Monaghan, Bliwise, and Wein contributed to the content, drafting, and critical revisions of this correspondence.



Compliance with ethical standards

Conflicts of interest

Thomas Monaghan has nothing to disclose. Dr. Bliwise has served as a consultant for Merck, Jazz, Ferring, Eisai, and Respicardia and speaker for Merck within the last three years, outside the submitted work. Dr. Wein has served as an advisor/consultant for Avadel, GTX, Acquinox, Urovant, Medtronic, and Serenity within the last three years, outside the submitted work.

Ethical approval

This correspondence was written in accordance with the Ethical Standards outlined by the Journal of Endocrinological Investigation.

Informed consent



  1. 1.
    Christ-Crain M, Fenske WK (2019) Copeptin in the differential diagnosis of hypotonic polyuria. J Endocrinol Invest. [Epub ahead of print]
  2. 2.
    Winzeler B, Cesana-Nigro N, Refardt J et al (2019) Arginine-stimulated copeptin measurements in the differential diagnosis of diabetes insipidus: a prospective diagnostic study. Lancet 394(10198):587–595CrossRefGoogle Scholar
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    Cornu JN, Abrams P, Chapple CR et al (2012) A contemporary assessment of nocturia: definition, epidemiology, pathophysiology, and management—a systematic review and meta-analysis. Eur Urol 62(5):877–890CrossRefGoogle Scholar

Copyright information

© Italian Society of Endocrinology (SIE) 2019

Authors and Affiliations

  1. 1.Department of UrologyState University of New York Downstate Health Sciences UniversityBrooklynUSA
  2. 2.Department of NeurologyEmory University School of MedicineAtlantaUSA
  3. 3.Department of UrologyPerelman School of Medicine at the University of PennsylvaniaPhiladelphiaUSA

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