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Disparities in Sepsis Mortality by Region, Urbanization, and Race in the USA: a Multiple Cause of Death Analysis

  • Funmilola OgundipeEmail author
  • Vijay Kodadhala
  • Temitayo Ogundipe
  • Alem Mehari
  • Richard Gillum
Article

Abstract

Purpose

To assess gender, race/ethnicity, and geographic disparities in sepsis-associated mortality.

Materials and Methods

The US data for multiple causes of death (MCOD) for years 2013–2016 were used to determine numbers of deaths and age-adjusted rates for sepsis as underlying or contributing cause of death using the International Classification of Diseases–10 (ICD-10) codes for non-Hispanic blacks (NHB) and whites (NHW) aged 15 years and older.

Results

There were a total of 746,725 sepsis-associated deaths. Among females, age-adjusted death rate for NHB was 88.6 (95% CI 87.8–89.3) and for NHW, 55.4 (95% CI 55.1–55.6). Among males, age-adjusted death rate for NHB was 115.2 (95% CI 114.1–116.3) and for NHW, 69.5 (95% CI 69.2–69.8). Rates were generally higher in divisions of the south region (West South Central in NHB). Within the South, NHW and NHB who resided in non-metropolitan areas had the highest rates, while the lowest were in suburban metropolitan areas.

Conclusions

Sepsis-related MCOD mortality rates were highest in males, in NHB, in the South region, and, within the South, non-metropolitan areas.

Keywords

Sepsis Septicemia Systemic inflammatory response syndrome Ethnic groups Race 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Supplementary material

40615_2018_553_MOESM1_ESM.docx (23 kb)
ESM 1 (DOCX 23 kb)

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Copyright information

© W. Montague Cobb-NMA Health Institute 2019

Authors and Affiliations

  1. 1.Howard University HospitalWashingtonUSA
  2. 2.Howard University College of MedicineWashingtonUSA

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