Placento-Cranial Adhesion: A New Syndromic Association

  • Bal ChanderEmail author
  • Daisy Dwivedi
  • Sita Thakur
  • Suman Yadav
Original Article


Cases of placento-cranial adhesion are rare and most of them are incompatible with life. A few case reports in the literature have included such cases under the overarching rubric of amniotic band syndrome. We present autopsy findings of four cases with gestation period ranging from 16 to 21 weeks. All of them displayed placenta-cranial adhesion, low weight for gestation, absence of flat bones of skull, anencephaly, dysmorphic facial features, short umbilical cord and limb/digit amputation with oligohydrambios. Three out of four showed nasal groove. We propose that there are grounds for syndromic association of the features mentioned above. Furthermore, it is important that whenever such cases are identified termination of pregnancy should be considered. The article also underscores the importance of fetal autopsies.


Fetus Adhesion Fatal 


Compliance with ethical standards

Conflict of interest

There is no conflict of interest. Furthermore the study was not funded by any organization.

Ethical approval

Ethical approval was taken from Institutional ethical committee. We in Dr Rajendra Prasad Government Medical College regularly perform fetal autopsies.


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Copyright information

© Society of Fetal Medicine 2019

Authors and Affiliations

  1. 1.Department of PathologyDr. Rajendra Prasad Government Medical College, KangraTandaIndia
  2. 2.Department of AnatomyDr. Rajendra Prasad Government Medical College, KangraTandaIndia
  3. 3.Department of Obstetrics and GynecologyDr. Rajendra Prasad Government Medical College, KangraTandaIndia

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