World Allergy Organization Grading System for Systemic Allergic Reactions: it Is Time to Speak the Same Language When it Comes to Allergic Reactions
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Purpose of review
To discuss current methods for grading severe allergic reactions (SARs) in view of the new WAO modified classification system.
While there is not universally accepted system for classifying SAR severity, and due to the high degree of heterogeneity and difficulties for comparisons between the various methods, the new WAO proposal is simple, suitable for use in clinical practice and universally applicable for all allergic reactions, covering the full spectrum of possible grades of severity.
There is a requirement for a simple and comprehensive system to classify systemic allergic reaction severity. The modification to WAO’s classification of SARs to allergen immunotherapy recently proposed by Cox et al. constitutes an important contribution in the goal of obtaining useful and helpful information for all involved stakeholders.
KeywordsAnaphylaxis Allergic reaction Severity Systemic allergic reaction
Compliance with ethical standards
Conflict of interest
Ignacio Ansotegui reports personal fees from Mundipharma, Roxall, Sanofi, MSD, Faes Farma, Hikma, UCB, and Astra Zeneca outside the submitted work. Mario Sanchez-Borges and Linda Cox declare no conflicts of interest relevant to this manuscript.
Human and animal rights and informed consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
References and Recommended Reading
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
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