Delirium and modified-release prednisone in an elderly woman with rheumatoid arthritis
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Delirium is an acute disturbance in attention and awareness, with fluctuating severity. A disturbance in cognition (e.g., memory deficit, disorientation, language, visual and spatial ability) represents an additional classification criterion. Alterations in sleep–wake cycle, perceptual disturbances, emotional lability, behavioral disturbances can be other supportive findings. According to the American Psychiatric Association (APA) Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) (DSM-5), there must be evidence from the history, physical examination or laboratory findings that all these disturbances are a direct consequence of: another medical condition, substance intoxication or withdrawal, exposure to a toxin, and multiple etiologies . In its fulfillment, predisposing (e.g., severity of an acute illness, sensory impairment, dehydration, multimorbidity) and precipitating factors (e.g., malnutrition, bladder cathether, polypharmacy with prescription...
KeywordsDelirium Modified-release prednisone Rheumatoid arthritis Neuroinflammation
The author thanks Dr. M. Papa, psychiatrist, and Dr. A. Mosca, general practitioner, for their precious collaboration.
Compliance with ethical standards
Conflict of interest
The author declares no conflict of interest.
The author declares that the case report was carried out in compliance with the Helsinki declaration.
Written informed consent was obtained from the patient for publication of this case report. A copy of the written consent may be requested from the author.